Immunosenescence refers to the immune system changes observed in individuals over 50 years old, characterized by diminished immune response and chronic inflammation.Recent investigations have highlighted similar immune alterations in patients with reduced kidney function.The immune system and kidney function have been found to be closely interconne
Sarah Shrader1,2, Ann M Rodden1, Lisa Carroll3, Lars E Peterson11Medical University of South Carolina, Department of Family Grinder Medicine, Charleston, SC, USA; 2South Carolina College of Pharmacy, Department of Clinical Pharmacy and Outcomes Sciences, Charleston, SC, USA; 3Spartanburg Regional Family Medicine Residency Program, Department of Fam
Abstract Multiple myeloma (MM) is a heterogeneous disease characterized by frequent MYC translocations.Sporadic MYC activation in the germinal center of genetically engineered Vk*MYC mice is sufficient to induce plasma cell tumors in which a variety of secondary mutations are spontaneously acquired and selected over time.Analysis of 119 Vk*MYC myel
A general-purpose Global Research Data Infrastructure (GRDI) for all sciences and research purposes is not conceivable for the next decade as there Diffusers are too many discipline-specific modalities that currently prevail for such generalisation efforts to be effective.On the other hand, a more pragmatic approach is to start from what currently